In this paper, the relevant articles in the field of ecological environment and human well-being from 2001 to 2020 collected in the Web of Science (WOS) core collection database are taken as the research object, combined with bibliometrics, visual analysis and other methods, to analyze the international research progress in this field. In the past 20 years, with the rapid degradation of the global ecological environment, more and more attention has been paid to the exploration of the research field of ecological environment and human well-being, and relevant theoretical and practical research has been continuously carried out. This field has developed rapidly, and the number of articles published has shown a linear and rapid upward trend. American and European countries have a great impact on this field, while the United States, Britain, Germany, Australia, China and Canada have published more than 200 papers in total, ranking top six. Among them, the United States ranked first in the number of articles and H-index, taking a leading position and having great influence. Although the number of articles in China ranks fifth, both H-index and citation frequency of articles are lower than other top 10 countries, indicating that the overall research level of China in this field needs to be improved. Chinese Academy of Sciences and Beijing Normal University are the two major China research institutions, ranking first and eighth respectively in terms of the number of articles. By terms clustering visualization analysis, the most concerned research hotspots mainly including urban green space system, ecosystem services, biodiversity, global change and food security. Sustainable development is increasingly becoming an crucial strategy to deal with global ecological and environmental problems and consequently promote the realization of a community of a shared future for mankind. In the future, we should build strategic framework for sustainable development, and strengthen disciplinary crossing and integration of multi-subject , monitor the global change rule. Furthermore, to keep people's welfare close to heart and pursue human development , we should pay more attention to the ecological system functions and effect of management or service, promote global joint protection actions, slow down the rate of biological decline, maintain biodiversity, and guarantee of food security at the macro level.