In this paper, the relevant articles in the field of ecological environment and human well-being from 2001 to 2020 collected in the Web of Science (WOS) core collection database are taken as the research object, combined with bibliometrics, visual analysis and other methods, to analyze the international research progress in this field. In the past 20 years, with the rapid degradation of the global ecological environment, more and more attention has been paid to the exploration of the research field of ecological environment and human well-being, and relevant theoretical and practical research has been continuously carried out. This field has developed rapidly, and the number of articles published has shown a linear and rapid upward trend. American and European countries have a great impact on  this field, while the United States, Britain, Germany, Australia, China and Canada have published more than 200 papers in total, ranking top six. Among them, the United States ranked first in the number of articles and H-index, taking a leading position and having great influence. Although the number of articles in China ranks fifth, both H-index and citation frequency of articles are lower than other top 10 countries, indicating that the overall research level of China in this field needs to be improved. Chinese Academy of Sciences and Beijing Normal University are the two major China research institutions, ranking first and eighth respectively in terms of the number of articles. By terms clustering visualization analysis, the most concerned research hotspots mainly including urban green space system, ecosystem services, biodiversity, global change and food security. Sustainable development is increasingly becoming an crucial strategy to deal with global ecological and environmental problems and consequently promote the realization of a community of a shared future for mankind. In the future, we should build strategic framework for sustainable development, and strengthen disciplinary crossing and integration of multi-subject , monitor the global change rule. Furthermore, to keep people's welfare close to heart and pursue human development , we should pay more attention to the ecological system functions and effect of management or service, promote global joint protection actions, slow down the rate of biological decline, maintain biodiversity, and guarantee of food security at the macro level.

The Tokyo Bay Area and the Guangdong-Hong Kong-Macao Greater Bay Area have some features in common (regional urbanity and original innovation). The research on the development trend and technological trend of the biomedical industry in the Tokyo Bay Area has reference and inspiration for the development of the biomedical industry in the Guangdong-Hong Kong-Macao Greater Bay Area. To this end, this paper uses the patent map analysis method to analyze the eight cities in the Tokyo Bay Area (Tokyo, Kanagawa, Ibaraki, Chiba, Chiba, Saitama, Tochigi, Yamanashi, Gunma) biopharmaceutical industry spatial characteristics were analyzed to reveal the biopharmaceutical patent spatial pattern and technology development trend in Tokyo Bay Area. Based on the analysis of the commonalities between the Tokyo Bay Area and the Guangdong Hong Kong Macao Greater Bay Area , we should attach importance to the internal circulation of the system and the cultivation of applied talents, accelerate the development of the biomedical industry in the Guangdong-Hong Kong-Macao Greater Bay Area, pays close attention to the convergence of innovative resources, promote the construction of a trillion-scale biomedical industry cluster in the Guangdong-Hong Kong-Macao Greater Bay Area, and strengthen the top-level design. Promoting the rationalization of the biomedical industry structure and coordinated regional development in the Guangdong-Hong Kong-Macao Greater Bay Area puts forward suggestions for the development of the biomedical industry in the Guangdong-Hong Kong-Macao Greater Bay Area.

Testimony to the diversity of ambitions and expectations for the bioeconomy are bioeconomy strategies of many countries and regions. The diversity of bioeconomic approaches often leads to a meta-level and concepts are described in very general terms. Then it often remains unclear what the bioeconomy does and what practical solutions it provides, the bioeconomy is often reduced to technologies. The central hypothesis of this article is that regionalization is a key to the concretization of bioeconomy concepts, and thus to real implementation and impact relevance. We propose the bioeconomy in a very open definition as the production and utilization of biological resources (including knowledge) to provide products, processes and services in all sectors within the framework of a sustainable economy. We then analyze relevant EU initiatives for the development of a sustainable bioeconomy and focus on the elements necessary for the development of a bioeconomy, including natural resources, human capital, industrial capital and technologies. Finally, regional industry clusters related to the bioeconomy are presented, with a focus on the BioökonomieREVIER (BÖR) and The Bioeconomy Science Center (BioSC) in Germany.

Recently, China’s first five-year plan for bioeconomy was released, which clearly identified bio-agriculture as one of the five key development areas. It not only cultivates new kinetic energy for the high-quality development of China’s agriculture, but also proposes a new direction for biotechnology innovation and bioindustry development. This paper expounds on the significance of agriculture as an important application scenario of the future bioeconomy. At the same time, it summarizes the development experience of the countries and regions represented by the United States and the European Union, such as the strategic policies and leading technologies of the bioeconomy. Based on analyzing the demand for biotechnology and bioeconomics in the process of China’s agriculture moving towards high-quality development, including the protection and utilization of germplasm resources, improving agricultural production efficiency, reducing agricultural emissions and ensuring the quality and safety of agricultural products and food, this paper proposes specific ways to give full play to the supporting role of bioeconomy in China’s high-quality agricultural development from three aspects: the improvement of agricultural biotechnology innovation capabilities, the integrated development of bio-agricultural industries and the creation of a favorable policy environment.

Ammonia is involved in agriculture and energy two core areas of bioeconomy. Clean ammonia, which does not depend on fossil resources and has no carbon dioxide emissions, can be used as a green fertilizer and provide a clean fuel with no carbon emissions, which can help promote the green transformation of agriculture and energy. This paper reviews the current status of bioammonia development in terms of technical advantages, major production technologies, applications, and commercialization challenges, and analyzes the feasibility of developing bioammonia as an important tool for the green transformation of agriculture and energy in the context of China's actual situation. Biorefining agricultural and forestry wastes to obtain high-value products such as biochar and pulp, bio-polyester, bio-fuel, etc. The production of clean ammonia from biochar to hydrogen using existing ammonia synthesis plants can compete economically with traditional fossil ammonia. China has 1 billion tons of usable agricultural and forestry waste as raw material security every year, and the production of 60 million tons of bio-ammonia can increase farmers’ income by 120 billion yuan, create 10000 billion yuan of output value, and reduce 200 million tons of carbon dioxide, which plays an important role in promoting the high-quality development of bio-economy.

The field of biotechnology is evolving rapidly and it has become one of the focal points of global scientific and technological competition. This paper mainly analyzes the development trend of global biotechnology, including major strategic development plans and initiatives and important research progress in frontier emerging fields, and makes suggestions for the development of biotechnology in China. Major economies in the world are carrying out strategic planning and project deployment from the perspective of national security to improve their domestic competitiveness in the biological fieldwhile paying more attention to the important role of biotechnology in promoting economic recovery and sustainable development in the post-epidemic era. From the perspective of research progress, the understanding and resolution of life have become more in-depth and systematic, which has promoted the development of life science. The ability to synthesize and modify organisms has been continuously enhanced, laying the foundation for the expansion of applications. Breakthroughs in engineering biology research and intelligent platform development have greatly promoted industrial development. Given the strategic planning, research layout, and global scientific and technological development trend of biotechnology in various countries, some suggestions are put forward from the aspects of research capacity building, discipline system optimization, talent team building, and industrialization application promotion to promote the innovation and development of the biotechnology in China.

In today's world, the information technology revolution is on the ascendant, and the digital economy is booming. However, the global economy has entered a recession period. It is difficult to overcome a series of problems such as life safety, food security, energy security, climate warming, etc. faced by human development only by relying on the digital economy. It is urgent to cultivate a new scientific and technological revolution and a new economic growth point. Since we published on Bio-economy in 2003, the progress of bio-technology in China and the world has obviously accelerated, and the new technological revolution of bio-technology and the new industrial revolution of bio-economy has accelerated. Human beings are entering the era of bio-economy. This paper focuses on the development trend of the bio-economy in the world. In this regard, this paper proposes that bio-technology will lead the new scientific and technological revolution, and the bio-economy will lead the new industrial revolution. Then, the concept and connotation of bio-economy are reviewed, the significant characteristics of the new scientific and technological revolution of bio-technology and the new industrial revolution of bio-economy are summarized, and the important role of bio-economy lies in: 1) Promote the fourth wave of economy and promote economic development; 2) Promote the fourth revolution in medicine and extend human life; 3) Promote the second green revolution and ensuring food security; 4) Promote technological change in manufacturing and develop green manufacturing; 5) Develop resources to protect diversity and improve the ecological environment; 6) Develop green energy and alleviate the pressure of energy security; 7) Defend against bio-terrorism and effectively ensure bio-security; 8) Reveal the laws of life, understand and transform and create creatures; 9) Adjust ethical concepts and prevent the abuse of bio-technology; 10) Develop cross-cutting technologies to give birth to a new scientific and technological revolution. The current problems in the development of bio-economy are: 1) Technological progress cannot meet the needs of the development of bio-economy; 2) The bioeconomic system is complex and diverse, which hinders the development of the bio-economy; 3) Technical barriers and trade barriers restrict the circulation and trade of biological products. Finally, combined with the current basic situation of the development of the world's bio-economy, the goals and countermeasures for future bio-economic development are proposed. These include: taking the bio-economy as a strategic industry for the world economy to get out of recession, taking basic research in life sciences as a breakthrough in the development of the bio-economy, creating an "International bio-economy federation", and promoting the coordinated development of the International bio-economy.

Climate change has been paid more and more attention by the international community, and has become a vital factor influencing countries to formulate their energy strategies. The energy utilization of straw conforms to the low-carbon and green development concept, and has great potential for carbon emission reduction. In order to analyze the development differences and clarify the  strengths and weaknesses of straw energy utilization technology between China and foreign countries, the research of straw energy utilization technology development in China and foreign countries based on patent data was analyzed from the aspects of annual application trend, regional distribution, technology distribution and main participants, meanwhile, China’s competitive position in the field was analyzed with the patent portfolio theory. The results demonstrate that China and foreign countries have their own characteristics in technology distribution, research activity, technology evolution and development direction. Straw energy utilization technology development in China is far more than that of foreign countries. However, China is still in the stage of technology research and development in straw energy utilization, universities and scientific research institutes provided rich technical reserve. The technology in China has changed from pyrolysis gasification technology to solidification technology and fermentation biogas technology as main part, with pyrolysis gasification technology, direct combustion technology and liquefaction technology developing in parallel, but liquefaction technology developing slowly. There still exists a large gap between European countries and the United States in terms of global protection, technology export, technology effects and industrialization. It has changed from solidification technology and direct combustion technology as main part, to solidification technology and liquefaction technology as main part, with liquefaction technology be the future developmental direction in foreign countries. In view of current situation and shortcomings, some suggestions on the development of straw energy utilization technology in China have been put forward.