The Tokyo Bay Area and the Guangdong-Hong Kong-Macao Greater Bay Area have some features in common (regional urbanity and original innovation). The research on the development trend and technological trend of the biomedical industry in the Tokyo Bay Area has reference and inspiration for the development of the biomedical industry in the Guangdong-Hong Kong-Macao Greater Bay Area. To this end, this paper uses the patent map analysis method to analyze the eight cities in the Tokyo Bay Area (Tokyo, Kanagawa, Ibaraki, Chiba, Chiba, Saitama, Tochigi, Yamanashi, Gunma) biopharmaceutical industry spatial characteristics were analyzed to reveal the biopharmaceutical patent spatial pattern and technology development trend in Tokyo Bay Area. Based on the analysis of the commonalities between the Tokyo Bay Area and the Guangdong Hong Kong Macao Greater Bay Area , we should attach importance to the internal circulation of the system and the cultivation of applied talents, accelerate the development of the biomedical industry in the Guangdong-Hong Kong-Macao Greater Bay Area, pays close attention to the convergence of innovative resources, promote the construction of a trillion-scale biomedical industry cluster in the Guangdong-Hong Kong-Macao Greater Bay Area, and strengthen the top-level design. Promoting the rationalization of the biomedical industry structure and coordinated regional development in the Guangdong-Hong Kong-Macao Greater Bay Area puts forward suggestions for the development of the biomedical industry in the Guangdong-Hong Kong-Macao Greater Bay Area.