Abstract: The “new infrastructure” has brought new opportunities for the development of major scientific & technological infrastructure. However, many unexpected situations will emerge amid rapid development. Therefore, systematic management and mechanism guarantees are urgent and necessary. As a key point of management of major scientific & technological infrastructure, risk management should be further strengthened and valued. This paper first lists some major scientific and technological risk events of research infrastructure, and analyzes the scientific, technical, economic and environmental impacts of these risk events. Then, this paper studies the risk management procedures and key processes of major scientific and technological infrastructure in the Department of Energy of the United States, including specific methods and measures adopted in risk planning, risk identification, risk analysis, and risk treatment. Based on current status of risk management of major scientific and technological infrastructure in China, several proposals are made, including establishing a risk management system that meets the characteristics of major scientific and technological infrastructure, comprehensively researching and identifying different types of risks and deploying in advance, strengthening process management, real time monitoring and adjusting risks and its dealing method, and carrying out facility construction management assessment, and regarding risk management as an important consideration.

Key words: Major Scientific &, Technological Infrastructure, Risk Management, Risk Identification, Risk Analysis, Addressing Risks